Welcome back to the Bluewell Peptides Weekly Roundup, your go-to update for peptide FAQs, industry news, and the latest insights from the research community.
Each week we answer real questions, highlight new studies, and share trends we’re seeing across the field.
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FAQs of the Week
1. What’s the “Wolverine Stack” (TB-500 + BPC-157)?
This regenerative pairing has been attracting a lot of interest:
- BPC-157 (5mg): Studied for gut, tendon, and ligament repair.
- TB-500 (5mg): Researched for cell migration, angiogenesis, and wound healing.
When stacked together, many researchers note complementary properties, earning it the nickname Wolverine Stack for its potential role in accelerated recovery.
2. How do CJC-1295 and Ipamorelin compare to other GHRPs and MK-677?
Both CJC-1295 (DAC or No DAC) and Ipamorelin are researched for stimulating growth hormone release in a way that aligns closely with the body’s natural GH pulse rhythm.
- Older GHRPs (e.g., GHRP-2, GHRP-6): Known to cause sharp GH spikes but often linked to side effects such as hunger, cortisol release, and prolactin elevation.
- MK-677 (Ibutamoren): A non-peptide GH secretagogue studied for its oral activity. While effective at elevating GH and IGF-1 levels, it is also associated with increased appetite, water retention, and sleep disruption.
- CJC-1295 + Ipamorelin: Deliver a smoother, more physiological GH release profile without the same unwanted effects.
👉 For these reasons, researchers often view the CJC-1295 + Ipamorelin combination as a cleaner, longer-term option in studies focused on aging, recovery, and body composition.
3. What is SS-31 and why is it making headlines?
SS-31 (Elamipretide) has recently gained FDA approval for use in rare mitochondrial disorders.
This mitochondria-targeted peptide is studied for its ability to bind cardiolipin, reduce oxidative stress, and support energy production.
Its approval signals the growing mainstream acceptance of peptide therapeutics.
4. What role does GHK-Cu play in research?
GHK-Cu (50mg) is widely studied in skin and hair research. It is associated with collagen synthesis, wound healing, and follicle stimulation — making it a popular choice in cosmetic and regenerative studies.
5. Can peptides influence tanning response?
Yes — Melanotan II (10mg) is studied for its effects on melanocortin receptors, with potential to influence melanin production.
Researchers are also exploring possible secondary effects on appetite and libido, though studies remain ongoing.
6. Why is Glutathione gaining attention?
Glutathione (15mg) is considered the body’s “master antioxidant” and is studied for detoxification, oxidative stress reduction, and immune support.
It continues to draw interest in anti-aging and wellness research.
Industry News
SS-31 (Elamipretide) Gains FDA Approval
In a landmark step, the FDA has approved SS-31 for mitochondrial disorders.
This is one of the clearest signals yet that peptide-based therapeutics are entering the mainstream medical arena.
GHRP Research Shifting to Cleaner Profiles
There is increasing focus on CJC-1295 + Ipamorelin combinations, reflecting a preference for peptides that align with natural GH release rather than sharp artificial spikes.
Recovery Peptides in the Spotlight
BPC-157 and TB-500 continue to be highlighted in preclinical research around musculoskeletal healing and post-injury repair.
Trends We’re Seeing
- The Wolverine Stack on the Rise TB-500 + BPC-157 are seeing growing demand from researchers focused on recovery and regeneration.
- CJC-1295 + Ipamorelin Preferred for Long-Term Studies These peptides are increasingly favored over older GHRPs and MK-677 for their smoother GH release profile.
- SS-31 Creates Buzz Post-Approval The FDA’s green light has spurred wider interest in mitochondria-targeted peptides.
- GHK-Cu Expands in Cosmetic Research Demand is growing for studies into skin elasticity, collagen support, and hair growth.
- Glutathione Stacks Emerging Researchers are combining Glutathione with other compounds in anti-aging and detoxification studies.
Closing Note
That wraps up Bluewell Weekly – Edition #2.
From the Wolverine Stack to SS-31’s FDA approval, this week has shown how diverse and fast-moving peptide research is becoming.
To explore our full peptide range, visit the Bluewell Peptides homepage.